Alfa1 antitrypsin

Also known as: α1-antitrypsin Serpin family A member 1 Alpha1 proteinase inhibitor A1PI A1AT

Active ingredient description

Human alpha1-proteinase inhibitor is understood to be the primary anti-protease in the lower respiratory tract, where it inhibits neutrophil elastase (NE). Normal healthy individuals produce sufficient alpha1-proteinase inhibitor to control the NE produced by activated neutrophils and are thus able to prevent inappropriate proteolysis of lung tissue by NE.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
B02AB02
Alfa1 antitrypsin
B Blood and blood forming organs → B02 Antihemorrhagics → B02A Antifibrinolytics → B02AB Proteinase inhibitors
Discover more medicines within B02AB02

Medicines

Alfa1 antitrypsin is the active ingredient of these drugs:

Drug
Countries
ALFALASTIN

France

GLASSIA

United States

PROLASPLAN

Spain

PROLASTIN

Austria France Ireland Netherlands

PROLASTIN-C

Brazil Canada United States

PROLASTINA

Spain

RESPREEZA

Austria Cyprus France Ireland Lithuania

VENTIA

Brazil

ZEMAIRA

Brazil

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
RESPREEZA Powder and solvent for solution
Summary of product characteristics (SPC)

Unique ingredient identifier (UNII)

F43I396OIS - .ALPHA.1-PROTEINASE INHIBITOR HUMAN

CAS registry number

9041-92-3 - Alpha-1-proteinase inhibitor

SNOMED-CT

14767006 - Human alpha1 proteinase inhibitor (substance)

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