Alpha-1 antitrypsin
Also known as: A1AT A1PI Alpha-1 proteinase inhibitor Serpin family A member 1 α1-antitrypsin
Brand names: GLASSIA PROLASTIN PROLASTIN-C RESPREEZA
Description
Human alpha1-proteinase inhibitor is understood to be the primary anti-protease in the lower respiratory tract, where it inhibits neutrophil elastase (NE). Normal healthy individuals produce sufficient alpha1-proteinase inhibitor to control the NE produced by activated neutrophils and are thus able to prevent inappropriate proteolysis of lung tissue by NE.
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