Alfacalcidol Other names: 1alpha-hydroxyvitamin D3 Alphacalcidol 1-hydroxycholecalciferol 1alpha-hydroxycholecalciferol
Chemical formula: C₂₇H₄₄O₂ Molecular mass: 400.637 g/mol PubChem compound: 5282181
Active ingredient description
Alfacalcidol is Vitamin D-hormone analog (an active metabolite of Vitamin D), which performs important functions in regulation of the calcium balance and the bone metabolism and is activated by the enzyme 25-hydroxylase (converted rapidly in the liver to 1,25-dihydroxyvitamin D) for systemic and in osteoblasts for local D-hormone actions.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| A11CC03 | Alfacalcidol | A Alimentary tract and metabolism → A11 Vitamins → A11C Vitamin A and D, incl. combinations of the two → A11CC Vitamin D and analogues |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| ONE-ALPHA Capsules | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| ONE-ALPHA Solution for injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |
Medicines
Alfacalcidol is an active ingredient of these brands:
Austria (AT)Brazil (BR)Canada (CA)Cyprus (CY)Estonia (EE)Finland (FI)France (FR)Germany (DE)Hong Kong (HK)Ireland (IE)Israel (IL)Japan (JP)Lithuania (LT)Malta (MT)Mexico (MX)Netherlands (NL)New Zealand (NZ)Poland (PL)Romania (RO)Singapore (SG)South Africa (ZA)Spain (ES)Tunisia (TN)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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