Alfacalcidol

Also known as: 1-hydroxycholecalciferol 1alpha-hydroxycholecalciferol 1alpha-hydroxyvitamin D3 Alphacalcidol

Active ingredient description

Alfacalcidol is Vitamin D-hormone analog (an active metabolite of Vitamin D), which performs important functions in regulation of the calcium balance and the bone metabolism and is activated by the enzyme 25-hydroxylase (converted rapidly in the liver to 1,25-dihydroxyvitamin D) for systemic and in osteoblasts for local D-hormone actions.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Alfacalcidol
A Alimentary tract and metabolism → A11 Vitamins → A11C Vitamin A and D, incl. combinations of the two → A11CC Vitamin D and analogues
Discover more medicines within A11CC03

Medicines

Alfacalcidol is the active ingredient of these drugs:

Drug
Countries

United Kingdom

United Kingdom

Poland

Hong Kong Singapore

South Africa

Estonia Germany

Cyprus

Austria Estonia Finland Netherlands Spain

Canada Cyprus Estonia Germany Hong Kong

Brazil

Germany

Germany

France Tunisia

South Africa

Alfacalcidol is also found within below combination drugs:

TEBONEVA

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Molecular mass: 400.637 g/mol

External identifiers

CAS Substance: 41294-56-8
DrugBank Drug: DB01436
KEGG Drug: D01518
RxNorm Ingredient: 12062
SNOMED-CT Concept: 11984007
Alfacalcidol (substance)
UNII Identifier: URQ2517572
ALFACALCIDOL