Alfacalcidol Other names: 1alpha-hydroxyvitamin D3 Alphacalcidol 1-hydroxycholecalciferol 1alpha-hydroxycholecalciferol

Chemical formula: C₂₇H₄₄O₂  Molecular mass: 400.637 g/mol  PubChem compound: 5282181

Therapeutic indications

Alfacalcidol is indicated for:

Renal osteodystrophy, hypoparathyroidism, rickets, osteomalacia

Population group: only adolescents (12 years - 18 years old) , adults (18 - 65 years old)

Alfacalcidol is indicated in all conditions where there is a disturbance of calcium metabolism due to impaired 1-α hydroxylation such as when there is reduced renal function.

The main indications are:

  • Renal osteodystrophy
  • Hypoparathyroidism
  • Nutritional and malabsorptive rickets and osteomalacia
  • Pseudo-deficiency (D-dependent) rickets and osteomalacia
  • Hypophosphataemic vitamin D resistant rickets and osteomalacia
  • Hyperparathyroidism (with bone disease)

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Renal osteodystrophy, hypoparathyroidism, rickets, osteomalacia

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old)

Alfacalcidol is indicated in all conditions where there is a disturbance of calcium metabolism due to impaired 1-α hydroxylation such as when there is reduced renal function.

The main indications are:

  • Renal osteodystrophy
  • Hypoparathyroidism
  • Nutritional and malabsorptive rickets and osteomalacia
  • Pseudo-deficiency (D-dependent) rickets and osteomalacia
  • Hypophosphataemic vitamin D resistant rickets and osteomalacia
  • Hyperparathyroidism (with bone disease)

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Renal osteodystrophy, hypoparathyroidism, rickets, osteomalacia

Population group: only elderly (65 years old or older)

Alfacalcidol is indicated in all conditions where there is a disturbance of calcium metabolism due to impaired 1-α hydroxylation such as when there is reduced renal function.

The main indications are:

  • Renal osteodystrophy
  • Hypoparathyroidism
  • Nutritional and malabsorptive rickets and osteomalacia
  • Pseudo-deficiency (D-dependent) rickets and osteomalacia
  • Hypophosphataemic vitamin D resistant rickets and osteomalacia
  • Hyperparathyroidism (with bone disease)

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Renal osteodystrophy, hypoparathyroidism, rickets, osteomalacia

Population group: only newborns (0 - 40 days old)

Alfacalcidol is indicated in all conditions where there is a disturbance of calcium metabolism due to impaired 1-α hydroxylation such as when there is reduced renal function.

The main indications are:

  • Renal osteodystrophy
  • Hypoparathyroidism
  • Nutritional and malabsorptive rickets and osteomalacia
  • Pseudo-deficiency (D-dependent) rickets and osteomalacia
  • Hypophosphataemic vitamin D resistant rickets and osteomalacia
  • Hyperparathyroidism (with bone disease)

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Alfacalcidol is contraindicated in the following cases:

Hypercalcaemia

Hypercalcemia

Pregnancy

Pregnancy

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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