Active ingredient description

Alosetron is a potent and selective 5-HT3 receptor antagonist. 5-HT3 receptors are ligand-gated cation channels that are extensively distributed on enteric neurons in the human gastrointestinal tract, as well as other peripheral and central locations.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
A Alimentary tract and metabolism → A03 Drugs for functional gastrointestinal disorders → A03A DRUGS FOR FUNCTIONAL BOWEL DISORDERS → A03AE Drugs acting on serotonin receptors
Discover more medicines within A03AE01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Structured Product Labeling (SPL/PLR)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₁₇H₁₈N₄O
Molecular mass: 294.351 g/mol

External identifiers

CAS Substance: 122852-42-0
DrugBank Drug: DB00969
KEGG Drug: D07129
PubChem Compound: 2099
RxNorm Ingredient: 85248
SNOMED-CT Concept: 116509006
Alosetron (substance)
UNII Identifier: 13Z9HTH115


Alosetron is an active ingredient of these brands:

United States (US)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.