Chemical formula: C₁₇H₁₈N₄O  Molecular mass: 294.351 g/mol  PubChem compound: 2099

Active ingredient description

Alosetron is a potent and selective 5-HT3 receptor antagonist. 5-HT3 receptors are ligand-gated cation channels that are extensively distributed on enteric neurons in the human gastrointestinal tract, as well as other peripheral and central locations.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A03AE01 Alosetron A Alimentary tract and metabolism → A03 Drugs for functional gastrointestinal disorders → A03A DRUGS FOR FUNCTIONAL BOWEL DISORDERS → A03AE Drugs acting on serotonin receptors
Discover more medicines within A03AE01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
LOTRONEX Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 122852-42-0
DrugBank Drug: DB00969
KEGG Drug: D07129
PubChem Compound: 2099
RxNorm Ingredient: 85248
SNOMED-CT Concept: 116509006
Alosetron (substance)
UNII Identifier: 13Z9HTH115


Alosetron is an active ingredient of these brands:

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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