Alprostadil

Active ingredient description

Alprostadil is chemically identical to prostaglandin E1, the actions of which include vasodilatation of blood vessels in the erectile tissues of the corpora cavernosa and increase in cavernosal artery blood flow, causing penile rigidity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Alprostadil
C Cardiovascular system → C01 Cardiac therapy → C01E Other cardiac preparations → C01EA Prostaglandins
Discover more medicines within C01EA01
Alprostadil
G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BE Drugs used in erectile dysfunction
Discover more medicines within G04BE01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK

Medicines

Alprostadil is the active ingredient of these drugs:

Drug
Countries

Ecuador

Austria

Turkey

Austria Ecuador

Turkey

Australia Austria Brazil Canada Cyprus

France Tunisia United States

Turkey

Japan

Austria

Austria Canada Estonia Finland Ireland

Japan

Austria Romania

Austria Brazil Poland Turkey

Canada Estonia Hong Kong Netherlands New Zealand

France

Estonia Finland

Lithuania Romania

Estonia

Estonia United Kingdom

Spain

Austria Cyprus Finland France Ireland

Poland

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂₀H₃₄O₅
Molecular mass: 354.487 g/mol

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 745-65-3
DrugBank Drug: DB00770
KEGG Drug: D00180
PubChem Compound: 5280723
RxNorm Ingredient: 598
SNOMED-CT Concept: 386972003
Alprostadil (substance)
SNOMED-CT Concept: 48988008
Alprostadil (substance)
UNII Identifier: F5TD010360
ALPROSTADIL