Aluminium chloride

Chemical formula: AlCl₃  Molecular mass: 133.341 g/mol  PubChem compound: 24012

Active ingredient description

Aluminium chloride hexahydrate acts locally, in the stratum comeum and in the terminal duct, to relieve hyperhidrosis. It is is acidic and is thought to act by diffusing into the sweat ducts where on neutralisation it forms gelatinous hydroxides which obstruct the flow of sweat.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D10AX01 Aluminium chloride D Dermatologicals → D10 Anti-acne preparations → D10A Anti-acne preparations for topical use → D10AX Other anti-acne preparations for topical use
Discover more medicines within D10AX01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DICLOR Solution for topical application Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 7446-70-0
DrugBank Drug: DB11081
PubChem Compound: 24012
RxNorm Ingredient: 46241
SNOMED-CT Concept: 387372003
Aluminium chloride (substance)
UNII Identifier: 3CYT62D3GA


Aluminium chloride is an active ingredient of these brands:

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Nigeria (NG)

  • (combination) NEOFIDROL as Aluminium chlorhydroxide

Poland (PL)

Turkey (TR)

  • (combination) PERS-MANT as Aluminum hydroxychloride

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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