Aluminium chloride hexahydrate acts locally, in the stratum comeum and in the terminal duct, to relieve hyperhidrosis. It is is acidic and is thought to act by diffusing into the sweat ducts where on neutralisation it forms gelatinous hydroxides which obstruct the flow of sweat.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Aluminium chloride is the active ingredient of these drugs:
Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):