Ambrisentan

Active ingredient description

Ambrisentan is an orally active, propanoic acid-class, ERA selective for the endothelin A (ETA) receptor. Endothelin plays a significant role in the pathophysiology of PAH.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
C02KX02
Ambrisentan
C Cardiovascular system → C02 Antihypertensives → C02K Other antihypertensives → C02KX Antihypertensives for pulmonary arterial hypertension
Discover more medicines within C02KX02

Medicines

Ambrisentan is the active ingredient of these drugs:

Drug
Countries
BRIASETA

Estonia Ireland

LETAIRIS

United States

PULMORIS

Australia

VOLIBRIS

Australia Austria Brazil Canada Cyprus

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
VOLIBRIS Film-coated tablet
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

HW6NV07QEC - AMBRISENTAN

CAS registry number

177036-94-1 - ambrisentan

SNOMED-CT

428159003 - Ambrisentan (substance)

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