Chemical formula: C₂₂H₂₂N₂O₄ Molecular mass: 378.428 g/mol PubChem compound: 6918493
Ambrisentan is an orally active, propanoic acid-class, ERA selective for the endothelin A (ETA) receptor. Endothelin plays a significant role in the pathophysiology of PAH.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
|C Cardiovascular system → C02 Antihypertensives → C02K Other antihypertensives → C02KX Antihypertensives for pulmonary arterial hypertension
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
|VOLIBRIS Film-coated tablet
|European Medicines Agency (EU)
|MPI, EU: SmPC
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