Amifostine

Chemical formula: C₅H₁₅N₂O₃PS  Molecular mass: 214.223 g/mol  PubChem compound: 2141

Therapeutic indications

Amifostine is indicated for:

Reduction of side effects of cisplatin

Population group: only adults (18 - 65 years old)

Amifostine is indicated to reduce the cumulative renal toxicity associated with repeated administration of cisplatin in patients with advanced ovarian cancer.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Reduction of xerostomia in patients undergoing radiotherapy

Population group: only adults (18 - 65 years old)

Amifostine is indicated to reduce the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer, where the radiation port includes a substantial portion of the parotid glands.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Amifostine is contraindicated in the following cases:

Pregnancy

Lactation

Nursing Mothers

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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