Active ingredient description

Aminophylline is a soluble derivative of theophylline and is given for its theophylline activity. Aminophylline relaxes smooth muscle and relieves bronchial spasm. It stimulates the myocardium and reduces venous pressure in congestive heart failure, leading to a marked increase in cardiac output.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
R Respiratory system → R03 Drugs for obstructive airway diseases → R03D Other systemic drugs for obstructive airway diseases → R03DA Xanthines
Discover more medicines within R03DA05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₁₆H₂₄N₁₀O₄
Molecular mass: 420.426 g/mol

External identifiers

CAS Substance: 317-34-0
CAS Substance: 49746-06-7
DrugBank Drug: DB01223
KEGG Drug: D00227
PubChem Compound: 9433
RxNorm Ingredient: 689
SNOMED-CT Concept: 373508009
Aminophylline (substance)
UNII Identifier: 27Y3KJK423


Aminophylline is an active ingredient of these brands:

Brazil (BR)

Estonia (EE)

Finland (FI)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Mexico (MX)

Romania (RO)

South Africa (ZA)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.