Amphotericin B
Brand names: ABELCET AMBISOME FUNGIZONE
Therapeutic Indications
Amphotericin B is indicated for:
Mycosis in febrile neutropenia
Irrespective of gender only Children (1 year - 12 years old) , Adolescents (12 years - 18 years old) Adults (18 years old or older)
Amphotericin B is indicated in adults and children aged 1 month to 18 years old for the empirical treatment of presumed fungal infections in febrile neutropenic patients, where the fever has failed to respond to broad spectrum antibiotics and appropriate investigations have failed to define a bacterial or viral cause.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intravenous - 3 mg/kg once daily
Visceral leishmaniasis in immunosuppression
Irrespective of gender only Infants (40 days - 1 year old) , Children (1 year - 12 years old) , Adolescents (12 years - 18 years old) Adults (18 years old or older)
Amphotericin B is indicated for the treatment of visceral leishmaniasis in immunocompetent patients including both adults and children.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intravenous - 1.5-2 mg/kg once daily
Severe systemic and/or deep mycoses
Irrespective of gender only Infants (40 days - 1 year old) , Children (1 year - 12 years old) , Adolescents (12 years - 18 years old) Adults (18 years old or older)
Amphotericin B is indicated in adults and children aged 1 month to 18 years old for the treatment of severe systemic and/or deep mycoses.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intravenous - 1-3 mg/kg once daily
Mucormycosis
Irrespective of gender only Infants (40 days - 1 year old) , Children (1 year - 12 years old) , Adolescents (12 years - 18 years old) Adults (18 years old or older)
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Intravenous - 5 mg/kg once daily
Contraindications
Active ingredient Amphotericin B is contraindicated in the following cases:
Hypersensitivity to amphotericin B
No gender/age discrimination