Amphotericin B is a macrocyclic, polyene antifungal antibiotic produced by Streptomyces nodosus. The molecule is thought to act by binding to sterols in the fungal cell membrane, with a resulting change in membrane permeability, allowing leakage of a variety of small molecules.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Amphotericin B is the active ingredient of these drugs:
Brazil Canada France Mexico Netherlands
Estonia
Estonia
Austria Brazil Canada Cyprus Estonia
Estonia
Lithuania
Austria Estonia Lithuania
Ecuador
Ecuador Estonia
Estonia
Australia New Zealand
Ecuador
Canada Estonia Finland France Hong Kong
Estonia
Ecuador
Brazil
Amphotericin B is also found within below combination drugs: