Angiotensin II

Active ingredient description

Angiotensin II raises blood pressure by vasoconstriction and increased aldosterone release. Direct action of angiotensin II on the vessel wall is mediated by binding to the G-protein-coupled angiotensin II receptor type 1 on vascular smooth muscle cells, which stimulates Ca2+/calmodulin-dependent phosphorylation of myosin and causes smooth muscle contraction.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Angiotensin II
C Cardiovascular system → C01 Cardiac therapy → C01C Cardiac stimulants excl. cardiac glycosides → C01CX Other cardiac stimulants
Discover more medicines within C01CX09

Medicines

Angiotensin II is the active ingredient of these drugs:

Drug
Countries

Austria Ireland Lithuania Poland United States

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Structured Product Labeling (SPL/PLR)
US

Unique ingredient identifier (UNII)

M089EFU921 - ANGIOTENSIN II

CAS registry number

4474-91-3 - angiotensin II

SNOMED-CT

85267009 - Angiotensin II (substance)