Angiotensin II

Active ingredient description

Angiotensin II raises blood pressure by vasoconstriction and increased aldosterone release. Direct action of angiotensin II on the vessel wall is mediated by binding to the G-protein-coupled angiotensin II receptor type 1 on vascular smooth muscle cells, which stimulates Ca2+/calmodulin-dependent phosphorylation of myosin and causes smooth muscle contraction.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
C Cardiovascular system → C01 Cardiac therapy → C01C Cardiac stimulants excl. cardiac glycosides → C01CX Other cardiac stimulants
Discover more medicines within C01CX09

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Structured Product Labeling (SPL/PLR)

Chemical formula: C₅₀H₇₁N₁₃O₁₂
Molecular mass: 1,046.179 g/mol

External identifiers

CAS Substance: 4474-91-3
DrugBank Drug: DB11842
PubChem Compound: 172198
RxNorm Ingredient: 1999003
SNOMED-CT Concept: 85267009
Angiotensin II (substance)
UNII Identifier: M089EFU921


Angiotensin II is an active ingredient of these brands:

United States (US)

Austria (AT)

Estonia (EE)

Ireland (IE)

Lithuania (LT)

Poland (PL)

Romania (RO)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.