Angiotensin II

Active ingredient description

Angiotensin II raises blood pressure by vasoconstriction and increased aldosterone release. Direct action of angiotensin II on the vessel wall is mediated by binding to the G-protein-coupled angiotensin II receptor type 1 on vascular smooth muscle cells, which stimulates Ca2+/calmodulin-dependent phosphorylation of myosin and causes smooth muscle contraction.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
C Cardiovascular system → C01 Cardiac therapy → C01C Cardiac stimulants excl. cardiac glycosides → C01CX Other cardiac stimulants
Discover more medicines within C01CX09

Medicines

$substanceName is the active ingredient of these drugs:

Drug
Countries

Austria Estonia Ireland Lithuania Poland

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Structured Product Labeling (SPL/PLR)
US

External identifiers

CAS Substance: 4474-91-3
DrugBank Drug: DB11842
RxNorm Ingredient: 1999003
SNOMED-CT Concept: 85267009
Angiotensin II (substance)
UNII Identifier: M089EFU921
ANGIOTENSIN II