Antithymocyte immunoglobulin is a selective immunosuppressive agent mostly acting on T lymphocytes. Antithymocyte immunoglobulin is used for the prevention and treatment of graft rejection after solid organ transplantation, usually in combination with other immunosuppressive drugs.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| L04AA04 | Antithymocyte immunoglobulin (rabbit) | L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AA Selective immunosuppressants |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| ATGAM Concentrate for solution for infusion | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| THYMOGLOBULINE Powder for solution for infusion | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |
Antithymocyte immunoglobulin is an active ingredient of these brands:
Austria (AT)Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)Ecuador (EC)
Estonia (EE)France (FR)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Japan (JP)
Lithuania (LT)
Malta (MT)
Netherlands (NL)New Zealand (NZ)
Poland (PL)
Romania (RO)Singapore (SG)
South Africa (ZA)
Spain (ES)Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
United States (US)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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