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Apremilast

Description

Apremilast, an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4), works intracellularly to modulate a network of pro-inflammatory and anti-inflammatory mediators. PDE4 is a cyclic adenosine monophosphate (cAMP)-specific PDE and the dominant PDE in inflammatory cells.

ATC Classification

Code
Title
Category
L04AA32
Apremilast
L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AA Selective immunosuppressants

Trade names

Trade name
Countries

Australia Austria Canada Cyprus France

Product Monographs

Monograph
Type
Country
OTEZLA Film-coated tablets
MPI, EU: SmPC