Apremilast

Description

Apremilast, an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4), works intracellularly to modulate a network of pro-inflammatory and anti-inflammatory mediators. PDE4 is a cyclic adenosine monophosphate (cAMP)-specific PDE and the dominant PDE in inflammatory cells.

Medicine classification

ATC Code
Title
Class
Apremilast
L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AA Selective immunosuppressants

Medicines

Drug
Countries

Australia Austria Canada Cyprus France

Product monographs

Monograph
Type
Country

2D Molecule Structure

2D representation of molecule

Unique Ingredient Identifier (UNII)

UP7QBP99PN - APREMILAST

CAS Registry Number

608141-41-9 - apremilast

SNOMED-CT

703350008 - Apremilast (substance)