Apremilast
Active ingredient description
Apremilast, an oral small-molecule inhibitor of phosphodiesterase 4 (PDE4), works intracellularly to modulate a network of pro-inflammatory and anti-inflammatory mediators. PDE4 is a cyclic adenosine monophosphate (cAMP)-specific PDE and the dominant PDE in inflammatory cells.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
ATC code
Group title
Classification
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Title
Type
Country
Medicines
Apremilast is the active ingredient of these drugs:
Structural formula
Chemical formula: C₂₂H₂₄N₂O₇S
Molecular mass: 460.5 g/mol