Apremilast

Chemical formula: C₂₂H₂₄N₂O₇S  Molecular mass: 460.5 g/mol  PubChem compound: 11561674

Therapeutic indications

Apremilast is indicated for:

Psoriasis, psoriatic arthritis

Apremilast, alone or in combination with Disease Modifying Antirheumatic Drugs (DMARDs), is indicated for the treatment of active psoriatic arthritis (PsA) in adult patients who have had an inadequate response or who have been intolerant to a prior DMARD therapy.

Apremilast is indicated for the treatment of moderate to severe chronic plaque psoriasis in adult patients who failed to respond to or who have a contraindication to, or are intolerant to other systemic therapy including cyclosporine, methotrexate or psoralen and ultraviolet-A light (PUVA).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Apremilast is contraindicated in the following cases:

Pregnancy

Pregnancy

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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