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Asenapine

Description

The mechanism of action of asenapine is not fully understood. However, based on its receptor pharmacology, it is proposed that the efficacy of asenapine is mediated through a combination of antagonist activity at D2 and 5-HT2A receptors. Actions at other receptors e.g. 5-HT1A, 5-HT1B, 5-HT2C, 5-HT6, 5-HT7, D3, and a2-adrenergic receptors, may also contribute to the clinical effects of asenapine.

ATC Classification

Code
Title
Category
N05AH05
Asenapine
N Nervous system → N05 Psycholeptics → N05A Antipsychotics → N05AH Diazepines, oxazepines and thiazepines

Trade names

Trade name
Countries

Australia Canada United States

United States

Austria Cyprus

Product Monographs

Monograph
Type
Country
SYCREST Sublingual tablet
MPI, EU: SmPC
SAPHRIS Tablet
MPI, US: SPL/PLR
US