Azacitidine
Also known as: Azacytidine
Active ingredient description
Azacitidine is believed to exert its antineoplastic effects by multiple mechanisms including cytotoxicity on abnormal haematopoietic cells in the bone marrow and hypomethylation of DNA. The cytotoxic effects of azacitidine may result from multiple mechanisms, including inhibition of DNA, RNA and protein synthesis, incorporation into RNA and DNA, and activation of DNA damage pathways.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Medicines
Azacitidine is the active ingredient of these drugs:
Ecuador
Austria
Australia Hong Kong Singapore
Australia New Zealand
Austria Poland
Ecuador
Ecuador
Ecuador
Estonia Ireland Lithuania Poland United States
Ecuador
Australia Austria Brazil Canada Cyprus
Brazil
Ecuador
Hong Kong Singapore
Poland
Structural formula
Chemical formula: C₈H₁₂N₄O₅
Molecular mass: 244.205 g/mol