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Azilsartan medoxomil

Description

Azilsartan medoxomil is an orally active prodrug that is rapidly converted to the active moiety, azilsartan, which selectively antagonises the effects of angiotensin II by blocking its binding to the AT1 receptor in multiple tissues. Angiotensin II is the principal pressor agent of the RAAS, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium.

ATC Classification

Code
Title
Category
C09CA09
Azilsartan medoxomil
C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09C Angiotensin II antagonists, plain → C09CA Angiotensin II antagonists, plain

Trade names

Trade name
Countries

Austria Canada United Kingdom United States

Product Monographs

Monograph
Type
Country
EDARBI Tablet
MPI, EU: SmPC