Balsalazide

Chemical formula: C₁₇H₁₅N₃O₆  Molecular mass: 357.318 g/mol  PubChem compound: 6335412

Active ingredient description

Balsalazide consists of mesalazine linked to a carrier molecule (4-aminobenzoyl-ß-alanine) via an azo bond. Bacterial azo-reduction releases mesalazine as an active metabolite in the colon. Mesalazine is an intestinal anti-inflammatory agent acting locally on the colonic mucosa. Its precise mechanism of action is unknown.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A07EC04 Balsalazide A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07E Intestinal antiinflammatory agents → A07EC Aminosalicylic acid and similar agents
Discover more medicines within A07EC04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
COLAZIDE Capsule, hard Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 80573-04-2
DrugBank Drug: DB01014
KEGG Drug: D07488
PubChem Compound: 6335412
RxNorm Ingredient: 18747
SNOMED-CT Concept: 420557005
Balsalazide (substance)
UNII Identifier: P80AL8J7ZP
BALSALAZIDE

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