Baxdrostat
Chemical formula: C₂₂H₂₅N₃O₂ Molecular mass: 363.195 g/mol
Active ingredient description
Baxdrostat is an inhibitor of human aldosterone synthase. Aldosterone contributes to hypertension by promoting the retention of sodium and water by the kidneys, which increases blood volume and, consequently, raises blood pressure. Aldosterone can cause vascular dysfunction, inflammation, and fibrosis. Inhibition of aldosterone synthase by baxdrostat decreases plasma aldosterone concentrations, thereby reducing blood pressure.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| C02KN02 | C Cardiovascular system → C02 Antihypertensives → C02K Other antihypertensives → C02KN Other antihypertensives | |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| BAXFENDY Film-coated tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) |
Medicines
Baxdrostat is an active ingredient of these brands:
United States (US)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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