Bempedoic acid

Chemical formula: C₁₉H₃₆O₅  Molecular mass: 344.492 g/mol  PubChem compound: 10472693

Active ingredient description

Bempedoic acid is an adenosine triphosphate-citrate lyase (ACL) inhibitor that lowers low-density lipoprotein cholesterol (LDL-C) by inhibition of cholesterol synthesis in the liver.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C10AX15 C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AX Other lipid modifying agents
Discover more medicines within C10AX15

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
NILEMDO Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
NEXLETOL Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 738606-46-7
DrugBank Drug: DB11936
PubChem Compound: 10472693
RxNorm Ingredient: 2282403
SNOMED-CT Concept: 870523005
Bempedoic acid (substance)
UNII Identifier: 1EJ6Z6Q368
BEMPEDOIC ACID

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