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Therapeutic Indications

Betaine is indicated for:


Irrespective of gender only Children (1 year - 12 years old) , Adolescents (12 years - 18 years old) Adults (18 years old or older)

Adjunctive treatment of homocystinuria, involving deficiencies or defects in:

  • cystathionine beta-synthase (CBS),
  • 5,10-methylene-tetrahydrofolate reductase (MTHFR),
  • cobalamin cofactor metabolism (cbl).

Betaine should be used as supplement to other therapies such as vitamin B6 (pyridoxine), vitamin B12 (cobalamin), folate and a specific diet.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Oral - 100 mg/kg in 2 divided doses daily


Active ingredient Betaine is contraindicated in the following cases: