Betaine Other names: Betaine hydrochloride Trimethylglycine

Molecular mass: 117.146 g/mol  PubChem compound: 247

Therapeutic indications

Betaine is indicated for:

Homocystinuria

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Adjunctive treatment of homocystinuria, involving deficiencies or defects in:

  • cystathionine beta-synthase (CBS),
  • 5,10-methylene-tetrahydrofolate reductase (MTHFR),
  • cobalamin cofactor metabolism (cbl).

Betaine should be used as supplement to other therapies such as vitamin B6 (pyridoxine), vitamin B12 (cobalamin), folate and a specific diet.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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