Betaine
Brand names: CYSTADANE
Therapeutic Indications
Betaine is indicated for:
Homocystinuria
Irrespective of gender only Children (1 year - 12 years old) , Adolescents (12 years - 18 years old) Adults (18 years old or older)
Adjunctive treatment of homocystinuria, involving deficiencies or defects in:
- cystathionine beta-synthase (CBS),
- 5,10-methylene-tetrahydrofolate reductase (MTHFR),
- cobalamin cofactor metabolism (cbl).
Betaine should be used as supplement to other therapies such as vitamin B6 (pyridoxine), vitamin B12 (cobalamin), folate and a specific diet.
For this indication, the medical literature mentions below treatments (click for details):
Treatment 1: Oral - 100 mg/kg in 2 divided doses daily
Contraindications
Active ingredient Betaine is contraindicated in the following cases: