Chemical formula: C₇H₅BiO₄ Molecular mass: 362.093 g/mol PubChem compound: 16682734
Bismuth subsalicylate is a derivative of salicylic acid, with anti-inflammatory and bactericidal action. Bismuth subsalicylate has weak antacid properties. Bismuth subsalicylate is used as an antacid and antidiarrheal, and to treat temporary discomfort of the stomach and gastrointestinal tract, such as nausea, heartburn, indigestion, upset stomach, and diarrhea. Bismuth subsalicylate may exert its antidiarrhoeal action not only by stimulating absorption of fluid and electrolytes across the intestinal wall but also when hydrolysed to salicylic acid, by inhibiting synthesis of a prostaglandin responsible for intestinal inflammation and hypermotility.
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| PEPTI-CALM Oral suspension | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Bismuth subsalicylate is an active ingredient of these brands:
Malta (MT)Mexico (MX)
Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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