Bismuth subsalicylate

Chemical formula: C₇H₅BiO₄  Molecular mass: 362.093 g/mol  PubChem compound: 16682734

Active ingredient description

Bismuth subsalicylate is a derivative of salicylic acid, with anti-inflammatory and bactericidal action. Bismuth subsalicylate has weak antacid properties. Bismuth subsalicylate is used as an antacid and antidiarrheal, and to treat temporary discomfort of the stomach and gastrointestinal tract, such as nausea, heartburn, indigestion, upset stomach, and diarrhea. Bismuth subsalicylate may exert its antidiarrhoeal action not only by stimulating absorption of fluid and electrolytes across the intestinal wall but also when hydrolysed to salicylic acid, by inhibiting synthesis of a prostaglandin responsible for intestinal inflammation and hypermotility.

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PEPTI-CALM Oral suspension Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 14882-18-9
DrugBank Drug: DB01294
KEGG Drug: D00728
PubChem Compound: 16682734
RxNorm Ingredient: 19478
SNOMED-CT Concept: 82075003
Bismuth subsalicylate (substance)
UNII Identifier: 62TEY51RR1


Bismuth subsalicylate is an active ingredient of these brands:

Israel (IL)

Malta (MT)

Mexico (MX)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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