Chemical formula: C₅₅H₈₄N₁₇O₂₁S₃⁺  Molecular mass: 1,415.552 g/mol  PubChem compound: 5360373

Active ingredient description

Bleomycin is a mixture of basic, water-soluble glycopeptide-antibiotics with cytotoxic activity. Bleomycin acts by interacting with both single and double-stranded DNA (deoxyribonucleic acid) leading to both single and double-strand scission, which leads in turn to inhibition of cell division, inhibition of growth and inhibition of DNA synthesis. Bleomycin can also influence RNA (ribonucleic acid) and protein biosynthesis to a lesser extent.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L01DC01 Bleomycin L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01D Cytotoxic antibiotics and related substances → L01DC Other cytotoxic antibiotics
Discover more medicines within L01DC01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
BLEOMYCIN Powder for solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

2D molecular structure

2D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 11056-06-7
DrugBank Drug: DB00290
PubChem Compound: 5360373
RxNorm Ingredient: 1622
SNOMED-CT Concept: 372843005
Bleomycin (substance)
UNII Identifier: 40S1VHN69B


Bleomycin is an active ingredient of these brands:

Brazil (BR)

Ecuador (EC)

Estonia (EE)

Hong Kong (HK)


Lithuania (LT)

Malta (MT)

Netherlands (NL)

Poland (PL)

South Africa (ZA)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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