Brentuximab vedotin

Therapeutic indications

Brentuximab vedotin is indicated for:

Hodgkin lymphoma (HL) CD30+

Population group: only adults (18 years old or older)

Brentuximab vedotin is indicated for adult patients with previously untreated CD30+ Stage IV Hodgkin lymphoma (HL) in combination with doxorubicin, vinblastine and dacarbazine (AVD).

Brentuximab vedotin is indicated for the treatment of adult patients with CD30+ HL at increased risk of relapse or progression following autologous stem cell transplant (ASCT).

Brentuximab vedotin is indicated for the treatment of adult patients with relapsed or refractory CD30+ Hodgkin lymphoma (HL):

  1. following ASCT, or
  2. following at least two prior therapies when ASCT or multi -agent chemotherapy is not a treatment option.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Systemic anaplastic large cell lymphoma (sALCL)

Population group: only adults (18 years old or older)

Brentuximab vedotin is indicated for the treatment of adult patients with relapsed or refractory systemic anaplastic large cell lymphoma (sALCL).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Cutaneous T-cell lymphoma (CTCL) with CD30+

Population group: only adults (18 years old or older)

Brentuximab is indicated for the treatment of adult patients with CD30+ cutaneous T-cell lymphoma (CTCL) after at least 1 prior systemic therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Brentuximab vedotin is contraindicated in the following cases:

Bleomycin

Bleomycin

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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