Bromhexine
Chemical formula: C₁₄H₂₀Br₂N₂ Molecular mass: 376.13 g/mol PubChem compound: 2442
Active ingredient description
Bromhexine is an expectorant used in the treatment of respiratory disorders associated with viscid or excessive mucus. Bromhexine is a synthetic derivative of the herbal active ingredient vasicine. It has been shown to increase the proportion of serous bronchial secretion, making it more easily expectorated. It is indicated as “secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport”.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| R05CB02 | Bromhexine | R Respiratory system → R05 Cough and cold preparations → R05C Expectorants, excl. combinations with cough suppressants → R05CB Mucolytics |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| BISOLVON Oral solution | MPI, EU: SmPC | Health Products Regulatory Authority (IE) |
Medicines
Bromhexine is an active ingredient of these brands:
Austria (AT)
Brazil (BR)
Croatia (HR)Cyprus (CY)
Ecuador (EC)
Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Israel (IL)Japan (JP)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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