Bromhexine

Chemical formula: C₁₄H₂₀Br₂N₂  Molecular mass: 376.13 g/mol  PubChem compound: 2442

Active ingredient description

Bromhexine is an expectorant used in the treatment of respiratory disorders associated with viscid or excessive mucus. Bromhexine is a synthetic derivative of the herbal active ingredient vasicine. It has been shown to increase the proportion of serous bronchial secretion, making it more easily expectorated. It is indicated as “secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport”.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R05CB02 Bromhexine R Respiratory system → R05 Cough and cold preparations → R05C Expectorants, excl. combinations with cough suppressants → R05CB Mucolytics
Discover more medicines within R05CB02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
BISOLVON Oral solution Health Products Regulatory Authority (IE) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 3572-43-8
CAS Substance: 611-75-6
DrugBank Drug: DB09019
KEGG Drug: D07542
PubChem Compound: 2442
RxNorm Ingredient: 1753
SNOMED-CT Concept: 708561003
Bromhexine (substance)
UNII Identifier: Q1J152VB1P
BROMHEXINE

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