Bupropion

Chemical formula: C₁₃H₁₈ClNO  Molecular mass: 239.741 g/mol  PubChem compound: 444

Therapeutic indications

Bupropion is indicated for:

Smoking cessation in nicotine-dependent patients

Population group: only adults (18 years old or older)

Bupropion is indicated as an aid to smoking cessation in combination with motivational support in nicotine-dependent patients.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Bupropion is contraindicated in the following cases:

Lactation

Lactation

Current seizure disorder, history of seizures

at least one of
Seizure disorder
† History of single seizure
H/O: febrile convulsions
H/O: epilepsy
Seizure

Central nervous system tumour

Neoplasm of central nervous system

Current or previous diagnosis of bulimia or anorexia nervosa

at least one of
Bulimia nervosa
Anorexia nervosa

Severe hepatic cirrhosis

Cirrhosis of liver

Monoamine oxidase inhibitors

Monoamine oxidase inhibitors (MAOIs)

History of bipolar disorder

Bipolar disorder

Patients undergoing abrupt withdrawal from medicinal products known to be associated with risk of seizures on withdrawal

at least one of
Alcohol withdrawal syndrome
Benzodiazepine withdrawal

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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