Calcitriol Other names: 1,25-dihydroxycholecalciferol 1,25-dihydroxyvitamin D3

Chemical formula: C₂₇H₄₄O₃  Molecular mass: 416.637 g/mol  PubChem compound: 5280453

Active ingredient description

Calcitriol is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In physiological amounts it augments the intestinal absorption of calcium and phosphate and plays a significant part in the regulation of bone mineralisation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A11CC04 Calcitriol A Alimentary tract and metabolism → A11 Vitamins → A11C Vitamin A and D, incl. combinations of the two → A11CC Vitamin D and analogues
Discover more medicines within A11CC04
D05AX03 Calcitriol D Dermatologicals → D05 Antipsoriatics → D05A Antipsoriatics for topical use → D05AX Other antipsoriatics for topical use
Discover more medicines within D05AX03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ROCALTROL Soft capsules Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
SILKIS Ointment Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 32222-06-3
DrugBank Drug: DB00136
KEGG Drug: D00129
PubChem Compound: 5280453
RxNorm Ingredient: 1894
SNOMED-CT Concept: 259333003
Calcitriol (substance)
UNII Identifier: FXC9231JVH

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