Captopril C₉H₁₅NO₃S

Active ingredient description

Captopril is a highly specific, competitive inhibitor of angiotensin-I converting enzyme (ACE inhibitors). Inhibition of ACE results in decreased plasma angiotensin-II, which leads to decreased vasopressor activity and to reduced aldosterone secretion. In patients with hypertension, captopril causes a reduction in supine and erect blood pressure, without inducing any compensatory increase in heart rate, nor water and sodium retention.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
C09AA01
Captopril
C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09A ACE inhibitors, plain → C09AA ACE inhibitors, plain
Discover more medicines within C09AA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
CAPOTEN Tablets
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₉H₁₅NO₃S
Molecular mass: 217.285 g/mol

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 62571-86-2
DrugBank Drug: DB01197
KEGG Drug: D00251
PubChem Compound: 44093
RxNorm Ingredient: 1998
SNOMED-CT Concept: 387160004
Captopril (substance)
UNII Identifier: 9G64RSX1XD
CAPTOPRIL

Medicines

Captopril is an active ingredient of these brands:

Australia (AU)

Brazil (BR)

Cyprus (CY)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Lithuania (LT)

Malta (MT)

Mexico (MX)

New Zealand (NZ)

Nigeria (NG)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

 
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