Captopril

Chemical formula: C₉H₁₅NO₃S  Molecular mass: 217.285 g/mol  PubChem compound: 44093

Therapeutic indications

Captopril is indicated for:

Essential hypertension

Population group: only adults (18 years old or older)

Captopril is indicated for the treatment of essential hypertension.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Myocardial infarction

Population group: only adults (18 years old or older)

Short-term (4 weeks) treatment: captopril is indicated in any clinically stable patient within the first 24 hours of an infarction.

Long-term prevention of symptomatic heart failure: captopril is indicated in clinically stable patients with asymptomatic left ventricular dysfunction.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Type I diabetic nephropathy

Population group: only adults (18 - 65 years old)

Captopril is indicated for the treatment of macroproteinuric diabetic nephropathy in patients with type I diabetes.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Essential hypertension

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Captopril is indicated for the treatment of essential hypertension.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Chronic heart failure

Population group: only adults (18 years old or older)

Captopril is indicated for the treatment of chronic heart failure.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Type I diabetic nephropathy

Population group: only elderly (65 years old or older)

Captopril is indicated for the treatment of macroproteinuric diabetic nephropathy in patients with type I diabetes.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Captopril is contraindicated in the following cases:

Angioedema

Angioedema

Pregnancy

Pregnancy

Lactation

Lactation

Aliskiren in diabetes mellitus or renal impairment (GFR <60 ml/min/1.73 m²)

Aliskiren and additionally at least one of
Diabetes mellitus



Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

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