Celecoxib

Chemical formula: C₁₇H₁₄F₃N₃O₂S  Molecular mass: 381.372 g/mol  PubChem compound: 2662

Active ingredient description

Celecoxib is an oral, selective, cyclooxygenase-2 (COX-2) inhibitor within the clinical dose range (200-400 mg daily). No statistically significant inhibition of COX-1 (assessed as ex vivo inhibition of thromboxane B2 [TxB2] formation) was observed in this dose range in healthy volunteers.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L01XX33 Celecoxib L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents
Discover more medicines within L01XX33
M01AH01 Celecoxib M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AH Coxibs
Discover more medicines within M01AH01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CELEBREX Capsule FDA, National Drug Code (US) MPI, US: SPL/PLR
CELEBREX Capsule, hard Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 169590-42-5
DrugBank Drug: DB00482
KEGG Drug: D00567
PubChem Compound: 2662
RxNorm Ingredient: 140587
SNOMED-CT Concept: 116081000
Celecoxib (substance)
UNII Identifier: JCX84Q7J1L
CELECOXIB

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