Celecoxib

Chemical formula: C₁₇H₁₄F₃N₃O₂S  Molecular mass: 381.372 g/mol  PubChem compound: 2662

Therapeutic indications

Celecoxib is indicated for:

Osteoarthritis

Population group: only adults (18 years old or older)

Celecoxib is indicated in adults for the symptomatic relief in the treatment of osteoarthritis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Rheumatoid arthritis

Population group: only adults (18 years old or older)

Celecoxib is indicated in adults for the symptomatic relief in the treatment of rheumatoid arthritis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Ankylosing spondylitis

Population group: only adults (18 years old or older)

Celecoxib is indicated in adults for the symptomatic relief in the treatment of ankylosing spondylitis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Celecoxib is contraindicated in the following cases:

Active peptic ulceration, gastrointestinal (GI) bleeding

at least one of
Peptic ulcer
Gastrointestinal hemorrhage

Pregnancy

Pregnancy

Lactation

Lactation

Ischaemic heart disease, peripheral arterial disease and/or cerebrovascular disease

at least one of
Ischemic heart disease
Peripheral arterial vascular disease
Cerebrovascular disease

Congestive heart failure (NYHA II-IV)

at least one of
Heart failure New York Heart Assosiation Class IΙΙ
Heart failure New York Heart Assosiation Class IV

Inflammatory bowel disease

Inflammatory bowel disease

Severe renal dysfunction

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Severe hepatic dysfunction

Hepatic failure stage IV

Non-steroidal anti-inflammatory drugs (NSAIDs) allergy

at least one of
NSAID-induced anaphylactoid reaction
NSAID-induced angio-oedema-urticaria

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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