Cetirizine

Chemical formula: C₂₁H₂₅ClN₂O₃  Molecular mass: 388.888 g/mol  PubChem compound: 2678

Active ingredient description

Cetirizine, a human metabolite of hydroxyzine, is a potent and selective antagonist of peripheral H1-receptors. In vitro receptor binding studies have shown no measurable affinity for other than Η1-receptors.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
R06AE07 Cetirizine R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AE Piperazine derivatives
Discover more medicines within R06AE07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ZIRTEK ALLERGY Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
REACTINE Tablet, Capsule, Syrup Health Products and Food Branch (CA) MPI, CA: SPM

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 83881-51-0
CAS Substance: 83881-52-1
DrugBank Drug: DB00341
PubChem Compound: 2678
RxNorm Ingredient: 20610
SNOMED-CT Concept: 372523007
Cetirizine (substance)
UNII Identifier: YO7261ME24
CETIRIZINE

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