Chloroquine

Chemical formula: C₁₈H₂₆ClN₃  Molecular mass: 319.872 g/mol  PubChem compound: 2719

Active ingredient description

Chloroquine binds to and alters the properties of DNA. Chloroquine also binds to ferriprotoporphyrin IX and this leads to lysis of the plasmodial membrane. In acute attacks of malaria, it interrupts erythrocytic schizogony of the parasite.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
P01BA01 Chloroquine P Antiparasitic products, insecticides and repellents → P01 Antiprotozoals → P01B Antimalarials → P01BA Aminoquinolines
Discover more medicines within P01BA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
AVLOCLOR Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 54-05-7
DrugBank Drug: DB00608
KEGG Drug: D02366
PubChem Compound: 2719
RxNorm Ingredient: 2393
SNOMED-CT Concept: 373468005
Chloroquine (substance)
UNII Identifier: 886U3H6UFF
CHLOROQUINE

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