Chemical formula: C₂₁H₃₀ClN Molecular mass: 331.207 g/mol
Colestyramine resin absorbs and combines with the bile acids in the intestine to form an insoluble complex which is excreted in the faeces. This results in an increased faecal loss of bile acids which leads to an increased oxidation of cholesterol to bile acids and a decrease in serum cholesterol levels and low density lipoprotein serum levels.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C10AC01 | Colestyramine | C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AC Bile acid sequestrants |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| QUESTRAN Powder for oral suspension | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Colestyramine is an active ingredient of these brands:
Australia (AU)Austria (AT)Brazil (BR)Canada (CA)Finland (FI)France (FR)Hong Kong (HK)
Ireland (IE)Japan (JP)Malta (MT)
Netherlands (NL)New Zealand (NZ)Nigeria (NG)Singapore (SG)
South Africa (ZA)Spain (ES)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
