Colestyramine Other names: Cholestyramine

Chemical formula: C₂₁H₃₀ClN  Molecular mass: 331.207 g/mol 

Therapeutic indications

Colestyramine is indicated for:

Primary prevention of coronary heart disease in primary hypercholesterolaemia

Population group: only adults (18 years old or older)

Primary prevention of coronary heart disease in men between 35 and 59 years of age and with primary hypercholesterolaemia who have not responded to diet and other appropriate measures.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hypercholesterolaemia Fredrickson's Type II

Population group: only adults (18 years old or older)

Reduction of plasma cholesterol in hypercholesterolaemia, particularly in those patients who have been diagnosed as Fredrickson’s Type II (high plasma cholesterol with normal or slightly elevated triglycerides).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Radiation-induced diarrhoea

Population group: only adults (18 years old or older)

Management of radiation-induced diarrhoea.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Hypercholesterolaemia Fredrickson's Type II

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Reduction of plasma cholesterol in hypercholesterolaemia, particularly in those patients who have been diagnosed as Fredrickson’s Type II (high plasma cholesterol with normal or slightly elevated triglycerides).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Pruritus associated with partial biliary obstruction and primary biliary cirrhosis

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Relief of pruritus associated with partial biliary obstruction and primary biliary cirrhosis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Pruritus associated with partial biliary obstruction and primary biliary cirrhosis

Population group: only adults (18 years old or older)

Relief of pruritus associated with partial biliary obstruction and primary biliary cirrhosis.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Diarrhoea associated with ileal resection, Crohn's disease, vagotomy, diabetic vagal neuropathy

Population group: only adults (18 years old or older)

Relief of diarrhoea associated with ileal resection, Crohn’s disease, vagotomy and diabetic vagal neuropathy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Radiation-induced diarrhoea

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Management of radiation-induced diarrhoea.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Diarrhoea associated with ileal resection, Crohn's disease, vagotomy, diabetic vagal neuropathy

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Relief of diarrhoea associated with ileal resection, Crohn’s disease, vagotomy and diabetic vagal neuropathy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Colestyramine is contraindicated in the following cases:

Hypersensitivity to colestyramine

Cholestyramine allergy

Biliary obstruction

Obstruction of biliary tree

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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