Cinacalcet

Chemical formula: C₂₂H₂₂F₃N  Molecular mass: 357.412 g/mol  PubChem compound: 156419

Active ingredient description

Cinacalcet is a calcimimetic agent which directly lowers PTH levels by increasing the sensitivity of the calcium sensing receptor to extracellular calcium. The reduction in PTH is associated with a concomitant decrease in serum calcium levels.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
H05BX01 Cinacalcet H Systemic hormonal preparations, excl. Sex hormones and insulins → H05 Calcium homeostasis → H05B Anti-parathyroid agents → H05BX Other anti-parathyroid agents
Discover more medicines within H05BX01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MIMPARA Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC
SENSIPAR Coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 226256-56-0
DrugBank Drug: DB01012
KEGG Drug: D03504
PubChem Compound: 156419
RxNorm Ingredient: 407990
SNOMED-CT Concept: 409392004
Cinacalcet (substance)
UNII Identifier: UAZ6V7728S
CINACALCET

Medicines

Cinacalcet is an active ingredient of these brands:

United States (US)

Austria (AT)

  • CINGLAN as CINACALCET HYDROCHLORIDE
  • MIMPARA as CINACALCET HYDROCHLORIDE

Brazil (BR)

  • CALT as CINACALCET HYDROCHLORIDE
  • MIMPARA as CINACALCET HYDROCHLORIDE
  • MISSORT as CINACALCET HYDROCHLORIDE

Canada (CA)

Croatia (HR)

  • MIMPARA as CINACALCET HYDROCHLORIDE

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

  • MIMPARA as CINACALCET HYDROCHLORIDE

Finland (FI)

  • MIMPARA as CINACALCET HYDROCHLORIDE
  • SINAFEX as CINACALCET HYDROCHLORIDE

France (FR)

  • MIMPARA as CINACALCET HYDROCHLORIDE

Hong Kong (HK)

  • REGPARA as CINACALCET HYDROCHLORIDE

Ireland (IE)

  • MIMPARA as CINACALCET HYDROCHLORIDE

Italy (IT)

  • MIMPARA as CINACALCET HYDROCHLORIDE

Japan (JP)

  • REGPARA as CINACALCET HYDROCHLORIDE

Lithuania (LT)

  • MIMPARA as CINACALCET HYDROCHLORIDE

Mexico (MX)

  • MIMPARA as CINACALCET HYDROCHLORIDE

Netherlands (NL)

  • MIMPARA as CINACALCET HYDROCHLORIDE

New Zealand (NZ)

Poland (PL)

Romania (RO)

  • MIMPARA as CINACALCET HYDROCHLORIDE

Singapore (SG)

  • REGPARA as CINACALCET HYDROCHLORIDE

South Africa (ZA)

Spain (ES)

  • MIMPARA as CINACALCET HYDROCHLORIDE

Turkey (TR)

  • CINESET as CINACALCET HYDROCHLORIDE
  • CYNACAL as CINACALCET HYDROCHLORIDE
  • MIMPARA as CINACALCET HYDROCHLORIDE
  • NEFROSET as CINACALCET HYDROCHLORIDE
  • PIMARO as CINACALCET HYDROCHLORIDE
  • VISCAP as CINACALCET HYDROCHLORIDE

United Kingdom (UK)

  • MIMPARA as CINACALCET HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.