Cinnarizine
Chemical formula: C₂₆H₂₈N₂ Molecular mass: 368.524 g/mol PubChem compound: 2761
Active ingredient description
Cinnarizine has been shown to be a non-competitive antagonist of the smooth muscle contractions caused by various vasoactive agents including histamine. Cinnarizine also acts on vascular smooth muscle by selectively inhibiting the calcium influx into depolarised cells, thereby reducing the availability of free Ca2+ ions for the induction and maintenance of contraction.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| N07CA02 | Cinnarizine | N Nervous system → N07 Other nervous system drugs → N07C Antivertigo preparations → N07CA Antivertigo preparations |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| STUGERON Tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |
Medicines
Cinnarizine is an active ingredient of these brands:
Austria (AT)
Brazil (BR)Croatia (HR)
Cyprus (CY)Ecuador (EC)Estonia (EE)Finland (FI)
Hong Kong (HK)
Ireland (IE)Israel (IL)Lithuania (LT)Malta (MT)Mexico (MX)Netherlands (NL)
Poland (PL)Romania (RO)Singapore (SG)South Africa (ZA)Spain (ES)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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