Cis-Diaminedichloroplatinum Other names: Cisplatin Platinum Ammine Chloride Trans-Diaminedichloroplatinum

Chemical formula: Clâ‚‚H₆Nâ‚‚Pt  Molecular mass: 300.05 g/mol  PubChem compound: 2767

Active ingredient description

Cisplatin is an anorganic substance containing a heavy metal [cis-diamminedichloroplatinum(II)]. This substance inhibits the DNA synthesis by realising transverse connections within and between the DNA strings. The protein and RNA synthesis is inhibited to a lesser extent.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L01XA01 Cisplatin L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XA Platinum compounds
Discover more medicines within L01XA01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CISPLATIN Concentrate for solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 15663-27-1
DrugBank Drug: DB00515
KEGG Drug: D00275
PubChem Compound: 2767
RxNorm Ingredient: 2555
SNOMED-CT Concept: 387318005
Cisplatin (substance)
UNII Identifier: Q20Q21Q62J
CISPLATIN

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