Clarithromycin

Chemical formula: C₃₈H₆₉NO₁₃  Molecular mass: 747.953 g/mol  PubChem compound: 84029

Active ingredient description

Clarithromycin is a semi-synthetic derivative of erythromycin A. It exerts its antibacterial action by selectively binding to the 50s ribosomal sub-unit of susceptible bacteria preventing translocation of activated amino acids. It inhibits the intracellular protein synthesis of susceptible bacteria.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01FA09 Clarithromycin J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01F Macrolides, lincosamides and streptogramins → J01FA Macrolides
Discover more medicines within J01FA09

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CLARITHROMYCIN Film-coated tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CLARITHROMYCIN Powder for concentrate for solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
KLERIMED Film coated tablet Υπουργείο Υγείας (CY) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 81103-11-9
DrugBank Drug: DB01211
KEGG Drug: D00276
PubChem Compound: 84029
RxNorm Ingredient: 21212
SNOMED-CT Concept: 387487009
Clarithromycin (substance)
UNII Identifier: H1250JIK0A
CLARITHROMYCIN

Medicines

Clarithromycin is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Finland (FI)

France (FR)

Germany (DE)

Ireland (IE)

Israel (IL)

Japan (JP)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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