Clomipramine Other names: Chlorimipramine Monochlorimipramine

Chemical formula: C₁₉H₂₃ClN₂  Molecular mass: 314.852 g/mol  PubChem compound: 2801

Therapeutic indications

Clomipramine is indicated for:

Depressive illness

Population group: only adults (18 years old or older)

In the management of endogenous depression including manic depression, periodic and involutional depression, reactive and neurotic depression.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Obsessional and phobic states

Population group: only adults (18 years old or older)

Anxiety disorder

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Cataplexy associated with narcolepsy

Population group: only adults (18 years old or older)

at least one of
Cataplexy and narcolepsy
Cataplexy

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Clomipramine is contraindicated in the following cases:

Monoamine oxidase inhibitors

Monoamine oxidase inhibitors (MAOIs)

Lactation

Lactation

Myocardial infarction

Myocardial infarction

Retention of urine

Retention of urine

Cardiac arrhythmias

Arrhythmia

Mania

Mania

Severe liver disease

Hepatic failure stage IV

Narrow-angle glaucoma

Angle-closure glaucoma

Congenital QT syndrome

Congenital long QT syndrome

Antiarrhythmics

Antiarrhythmics, class I and III

Diuretics

Diuretics

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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