Collagenase Other names: Collagenase clostridium histolyticum Clostridiopeptidase

PubChem compound: 44384985

Therapeutic indications

Collagenase is indicated for:

Dupuytren's contracture

Population group: only adults (18 years old or older)

Collagenase is indicated for the treatment of Dupuytren’s contracture in adult patients with a palpable cord.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Peyronie's disease

Population group: only adults (18 years old or older)

Collagenase is indicated for the treatment of adult men with Peyronie’s disease with a palpable plaque and curvature deformity of at least 30 degrees at the start of therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Chronic dermal ulcers, burned areas

Population group: only adults (18 years old or older)

Collagenase ointment is indicated for debriding chronic dermal ulcers and severely burned areas.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Collagenase is contraindicated in the following cases:

Peyronie's plaques that involve the penile urethra

Induratio penis plastica and additionally Cavernous portion of urethra

Special penile conditions

at least one of
Thrombosis of penile vein
Congenital lateral curvature of penis
Mass of penis
Nicholas Favre disease

Tetracyclines

Tetracyclines

Pregnancy

Pregnancy

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Related medicines

Summary of Product Characteristics (SPC) 2020: XIAPEX Powder and solvent for solution for injection
Structured Product Labeling (SPL) 2019: COLLAGENASE SANTYL Ointment
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