Cytarabine

Chemical formula: C₉H₁₃N₃O₅  Molecular mass: 243.217 g/mol  PubChem compound: 6253

Active ingredient description

Cytarabine (ARA-C) is metabolised in vivo to ARA-CTP phosphorylated compound. This competitively inhibits DNA polymerase and may also inhibit certain acid kinase enzymes.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
L01BC01 Cytarabine L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BC Pyrimidine analogues
Discover more medicines within L01BC01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CYTARABINE Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 147-94-4
DrugBank Drug: DB00987
KEGG Drug: D00168
PubChem Compound: 6253
RxNorm Ingredient: 3041
SNOMED-CT Concept: 387511003
Cytarabine (substance)
UNII Identifier: 04079A1RDZ
CYTARABINE

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