Chemical formula: C₈₈H₁₀₀Cl₂N₁₀O₂₈ Molecular mass: 1,814.609 g/mol PubChem compound: 23724878
Dalbavancin is a bactericidal lipoglycopeptide. Its mechanism of action in susceptible Gram-positive bacteria involves interruption of cell wall synthesis by binding to the terminal D-alanyl-D-alanine of the stem peptide in nascent cell wall peptidoglycan, preventing cross-linking (transpeptidation and transglycosylation) of disaccharide subunits resulting in bacterial cell death.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| J01XA04 | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01X Other antibacterials → J01XA Glycopeptide antibacterials | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| XYDALBA Powder for concentrate for solution for infusion | European Medicines Agency (EU) | MPI, EU: SmPC |
Dalbavancin is an active ingredient of these brands:
United States (US)
Austria (AT)Estonia (EE)Finland (FI)France (FR)Ireland (IE)Lithuania (LT)Netherlands (NL)Poland (PL)Romania (RO)Spain (ES)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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