Delamanid

Chemical formula: C₂₅H₂₅F₃N₄O₆  Molecular mass: 534.492 g/mol 

Active ingredient description

The pharmacological mode of action of delamanid involves inhibition of the synthesis of the mycobacterial cell wall components, methoxy-mycolic and keto-mycolic acid. The identified metabolites of delamanid do not show anti-mycobacterial activity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J04AK06 J Antiinfectives for systemic use → J04 Antimycobacterials → J04A Drugs for treatment of tuberculosis → J04AK Other drugs for treatment of tuberculosis
Discover more medicines within J04AK06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DELTYBA Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC
DELTYBA Dispersible tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 681492-22-8
DrugBank Drug: DB11637
KEGG Drug: D09785
SNOMED-CT Concept: 714097004
Delamanid (substance)
UNII Identifier: 8OOT6M1PC7
DELAMANID

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