Delamanid

Chemical formula: C₂₅H₂₅F₃N₄O₆  Molecular mass: 534.492 g/mol 

Therapeutic indications

Delamanid is indicated for:

Multi-drug resistant tuberculosis (MDR-TB)

Population group: only adults (18 - 65 years old)

Delamanid is indicated for use as part of an appropriate combination regimen for pulmonary multi-drug resistant tuberculosis (MDR-TB) in adults when an effective treatment regimen cannot otherwise be composed for reasons of resistance or tolerability.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Multi-drug resistant tuberculosis (MDR-TB)

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Delamanid is indicated for use as part of an appropriate combination regimen for pulmonary multi-drug resistant tuberculosis (MDR-TB) in adolescents, children and infants with a body weight of at least 10 kg when an effective treatment regimen cannot otherwise be composed for reasons of resistance or tolerability.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Delamanid is contraindicated in the following cases:

Serum albumin <2.8 g/dL

Hypoalbuminemia

Strong inducers of CYP3A4

Strong potency CYP3A4 inducers

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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