Chemical formula: C₂₂H₂₄ClN₅O₂ Molecular mass: 425.911 g/mol PubChem compound: 3151
Domperidone is a dopamine antagonist with anti-emetic properties, Domperidone does not readily cross the blood-brain barrier. In domperidone users, especially in adults, extrapyramidal side effects are very rare, but domperidone promotes the release of prolactin from the pituitary.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A03FA03 | Domperidone | A Alimentary tract and metabolism → A03 Drugs for functional gastrointestinal disorders → A03F Propulsives → A03FA Propulsives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MOTILIUM Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Domperidone is an active ingredient of these brands:
Australia (AU)Austria (AT)Estonia (EE)France (FR)Germany (DE)Hong Kong (HK)
Israel (IL)Japan (JP)Lithuania (LT)Netherlands (NL)New Zealand (NZ)Nigeria (NG)South Africa (ZA)Spain (ES)Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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