Chemical formula: C₂₄H₃₀ClN₇O₄S Molecular mass: 548.06 g/mol PubChem compound: 10280735
Edoxaban is a highly selective, direct and reversible inhibitor of factor Xa, the serine protease located in the final common pathway of the coagulation cascade. Edoxaban inhibits free factor Xa, and prothrombinase activity. Inhibition of factor Xa in the coagulation cascade reduces thrombin generation, prolongs clotting time and reduces the risk of thrombus formation.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| B01AF03 | B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AF Direct factor Xa inhibitors | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| LIXIANA Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Edoxaban is an active ingredient of these brands:
United States (US)
Canada (CA)
Finland (FI)
France (FR)
Hong Kong (HK)
Israel (IL)
Italy (IT)
Japan (JP)
Netherlands (NL)
Romania (RO)
Spain (ES)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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