Eflornithine

Chemical formula: C₆H₁₂F₂N₂O₂  Molecular mass: 182.171 g/mol  PubChem compound: 3009

Active ingredient description

Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme involved in the production of the hair shaft by the hair follicle. Eflornithine has been shown to reduce the rate of hair growth.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D11AX16 Eflornithine D Dermatologicals → D11 Other dermatological preparations → D11A Other dermatological preparations → D11AX Other dermatologicals
Discover more medicines within D11AX16
L01XX79 L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents
Discover more medicines within L01XX79
P01CX03 Eflornithine P Antiparasitic products, insecticides and repellents → P01 Antiprotozoals → P01C Agents against leishmaniasis and trypanosomiasis → P01CX Other agents against leishmaniasis and trypanosomiasis
Discover more medicines within P01CX03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VANIQA Cream European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 70052-12-9
DrugBank Drug: DB06243
KEGG Drug: D07883
PubChem Compound: 3009
RxNorm Ingredient: 569
SNOMED-CT Concept: 372533004
Eflornithine (substance)
UNII Identifier: ZQN1G5V6SR
EFLORNITHINE

Medicines

Eflornithine is an active ingredient of these brands:

United States (US)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Austria (AT)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Canada (CA)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Croatia (HR)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Estonia (EE)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Finland (FI)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

France (FR)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Ireland (IE)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Israel (IL)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Italy (IT)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Lithuania (LT)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Netherlands (NL)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Poland (PL)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Romania (RO)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Spain (ES)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Turkey (TR)

  • EFLORIN as EFLORNITHINE HYDROCHLORIDE

United Kingdom (UK)

  • VANIQA as EFLORNITHINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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