Ferric citrate Other names: Iron(III) citrate

Chemical formula: C₆H₇FeO₈ Molecular mass: 967.803 g/mol

Active ingredient description

Ferric citrate coordination complex is specifically designed to have a high surface area and a defined molar ratio of ferric iron to citrate. The high surface area of ferric citrate coordination complex impacts ferric iron solubility at physiological pH and allows part of ferric iron to be absorbed and supply iron to the metabolic pathway. Ferric citrate coordination complex has a dual mechanism of action, one that is associated with providing a source of ferric iron and one associated with decreasing the absorption of phosphorous.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group		Classification
V03AE08		V Various → V03 All other therapeutic products → V03A All other therapeutic products → V03AE Drugs for treatment of hyperkalemia and hyperphosphatemia
Discover more medicines within V03AE08

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document	Type	Information Source
AURYXIA Film-coated tablet	MPI, US: SPL/PLR	FDA, National Drug Code (US)
XOANACYL Film-coated tablet	MPI, EU: SmPC	European Medicines Agency (EU)

Medicines

Ferric citrate is an active ingredient of these brands:

Austria (AT)

FEXERIC as Iron(III) citrate
XOANACYL as Iron(III) citrate

Estonia (EE)

FEXERIC as Iron(III) citrate
XOANACYL as Iron(III) citrate

Ireland (IE)

FEXERIC as Iron(III) citrate

Israel (IL)

(combination) FERROCAL as FERROUS CITRATE

Italy (IT)

XOANACYL as Iron(III) citrate

Japan (JP)

FERROMIA as SODIUM FERROUS CITRATE
RIONA as FERRIC CITRATE TRIHYDRATE

Lithuania (LT)

FEXERIC as Iron(III) citrate
XOANACYL as Iron(III) citrate

Poland (PL)

FEXERIC as Iron(III) citrate

Singapore (SG)

FERROCYTE as SODIUM FERROUS CITRATE

Turkey (TR)

FERRISITA

United States (US)

AURYXIA as TETRAFERRIC TRICITRATE DECAHYDRATE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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